A global bioscience dedicated to testing, evaluating, and approving the quality of innovative ingredients,
through 30 different tests.
PHZON Group, LLC USA is committed to innovation and excellence. For more detailed information on the tests and composition of CREATEST30®, please refer to the technical documentation provided by PHZON Group, LLC USA or contact our team of specialists.
Quality You Can
Count on 30 Times,
Trust in Every Test.
PHZON Group, LLC USA is committed to innovation and excellence. For more detailed information on the tests and composition of CREATEST30®, please refer to the technical documentation provided by PHZON Group, LLC USA or contact our team of specialists.
Elevated by 30 Rigorous Tests
Creatine monohydrate is widely recognized for its ability to enhance physical performance, especially in high-intensity and short-duration exercises. CREATEST30® uses pharmaceutical-grade raw materials, guaranteeing the absence of contaminants and impurities. Each batch undergoes a spectrum of chemical and microbiological analyses. Additionally, the product is routinely audited by independent laboratories, providing an additional level of quality assurance and compliance.
30 Tests for Peak Performance
CREATEST30® is a premium and exclusive creatine monohydrate supplement, tested, evaluated, and approved by PHZON Group, LLC USA. This product undergoes a rigorous evaluation process, involving thirty distinct quality tests, ensuring its purity, efficacy, and safety for human consumption.
1. Assay
(HPLC)
Precise quantification of the active ingredient is conducted via High-Performance Liquid Chromatography (HPLC), essential for ensuring bioavailability and therapeutic efficacy. Advanced HPLC systems, such as the Waters ACQUITY UPLC or Agilent InfinityLab LC Series, equipped with high-sensitivity UV-Vis detectors, provide accurate analysis of bioactive compound concentration, promoting strict control over potency and pharmacodynamic response.
2. Product Purity
(HPLC)
Product purity is assessed using HPLC, identifying and quantifying impurities that may interfere with pharmacological activity. Utilizing instruments like the Shimadzu Nexera XR, with diode array detectors (DAD), this analysis allows for the detection of trace-level impurities, minimizing toxicological risks and ensuring chemical conformity for predictable pharmacokinetics.
3. Creatine Content
(HPLC)
This test measures creatine concentration using HPLC to ensure accurate dosage, crucial for optimizing cellular energy metabolism and muscle performance. Systems like the Thermo Scientific Vanquish Core enable detection of minimal concentration variations, ensuring effectiveness in ergogenic support.
4. Appearance
Detailed visual inspection is performed with high-resolution digital inspection cameras, such as the Leica DMS1000, ensuring the product meets expected aesthetic characteristics. Any deviation in appearance may suggest chemical instability or contamination, potentially compromising clinical acceptance and batch-to-batch consistency.
5. Appearance, Color
Color verification is conducted with color spectrophotometers, such as the Konica Minolta CM-700d, which precisely quantify color using CIE Lab coordinates. This analysis detects changes that could indicate degradation, ensuring chromatic uniformity and product stability.
6. Appearance, Odor
Odor evaluation is conducted using electronic noses, such as the Alpha MOS HERACLES Neo, which detect volatile compounds indicative of contamination or degradation. The precision of this equipment is crucial for confirming product integrity and ensuring the absence of odors that could impact safety and tolerability.
7. Bulk Density
(USP)
Bulk density is measured using the Quantachrome Autotap, ensuring precise packing volume calculation, which is essential for uniform dosing and solubility. This control optimizes handling and transport, providing predictability in active ingredient release.
8. Loss on Drying
(USP)
Residual moisture analysis is performed with halogen drying balances, such as the Mettler Toledo HX204, which offer uniform heating for precise moisture control. This technique is critical for verifying product stability, preventing microbial growth, and ensuring durability.
9. Particle Size USP32
(USP)
Particle size analysis, conducted with the Malvern Mastersizer 3000, is crucial for ensuring uniform dissolution and absorption, directly impacting bioavailability and clinical efficacy. This laser diffraction system provides precise particle size distribution, guaranteeing consistent absorption.
10. Related Impurities, Creatinine (HPLC)
Creatinine impurity analysis is performed using HPLC coupled with mass detectors, such as the Agilent 6545 LC/Q-TOF, to ensure it remains at trace levels, preventing adverse effects like nephrotoxicity. The precision of this system provides reliable detection for patient safety.
11. Related Impurities, Dihydrotriazine
(HPLC)
Using reverse-phase HPLC, such as the Waters Alliance HPLC equipped with fluorescence detectors, this test ensures that dihydrotriazine, a toxic impurity, is below acceptable limits. This technology minimizes the risk of interference with biological processes.
12. Related Impurities, Dicyandiamide
(HPLC)
Detection of dicyandiamide is carried out with UPLC systems like the Thermo Scientific UltiMate 3000, ensuring trace levels are absent to avoid toxicity. High-resolution, rapid analysis is essential for toxicological safety.
13. Residue on Ignition
(USP)
The analysis of inorganic residues post-combustion is conducted in muffle furnaces like the Carbolite Gero ELF, ensuring that metals or contaminants are not present in the final product, thus maintaining purity and compliance with safety standards.
14. Total Heavy Metals as Lead (USP <231> ICP-MS)
Detection of heavy metals using the PerkinElmer NexION 5000 ICP-MS ensures precision at sub-ppb levels, confirming that lead, a neurotoxin, remains at safe concentrations. This highly sensitive equipment is essential for long-term toxicological safety.
15. Sulfate
(USP)
Sulfate analysis is conducted with ion chromatography systems, such as the Metrohm 940 Professional IC Vario, ensuring compliance with concentration requirements to maintain the product's chemical properties and expected bioavailability.
16. Arsenic
(ICP-MS)
Arsenic detection with ICP-MS, using instruments like the Thermo Scientific iCAP RQ, ensures this toxic element remains at safe levels, crucial for avoiding hematotoxic and carcinogenic effects. The high sensitivity of this equipment enables rigorous analysis.
17. Cadmium
(ICP-MS)
The Agilent 8900 Triple Quadrupole ICP-MS precisely monitors cadmium levels, protecting against cumulative toxic effects and ensuring compliance with safety standards to prevent nephrotoxicity.
18. Lead
(ICP-MS)
Using the PerkinElmer NexION 2000, this test confirms minimal lead content, preventing neurotoxicity. The sensitive ICP-MS detection meets regulatory requirements with accuracy.
19. Mercury
(ICP-MS)
Mercury detection, essential due to its neurotoxic properties, is performed with the Agilent 7800 ICP-MS, providing high precision and minimizing interferences to ensure the product is free from contaminants that could impact the nervous and immune systems.
20. Fe Iron
(USP 233 ICP-MS)
Precise quantification of iron is conducted using the Shimadzu ICPMS-2030, an inductively coupled plasma mass spectrometer with exceptional sensitivity and selectivity. This equipment enables trace-level detection, ensuring iron concentrations stay within specified limits to avoid toxicity and support proper cellular metabolism.
21. Detection of Pesticides
(GC-MS)
Pesticide analysis using GC-MS, such as the Agilent 7890B GC paired with the 5977B MS, enables detection of toxic compounds with high specificity, ensuring the product is free from environmental contaminants.
22. Aflatoxin B1
(AOAC Modified)
Detection of aflatoxin B1, a carcinogenic mycotoxin, is conducted with HPLC using a fluorescence detector, such as the Waters 2475. This setup maximizes sensitivity, ensuring the product is safe for consumption.
23. Aerobic Plate Count
(USP 2021/2022)
Automated incubators like the BioMérieux TEMPO are used for microbial counting, confirming the product is free from bacterial contaminants, thereby minimizing infection risks and ensuring microbiological safety.
24. Listeria monocytogenes (USP)
Rapid detection of Listeria monocytogenes is performed using PCR with systems such as the Thermo Scientific SureTect, ensuring the absence of this dangerous pathogen, crucial for consumer protection.
25. Streptococcus haemolyticus beta
Microbiological analysis for Streptococcus is conducted on culture platforms like the Danisco LYOBAC, precisely monitoring for the presence of this pathogen and preventing infection risks.
26. Salmonella spp.
(USP 2022-Dec 2020)
Salmonella detection is carried out with real-time PCR systems, such as the 3M Molecular Detection System, allowing high-precision pathogen detection and ensuring the product’s microbiological safety.
27. E. Coli
(USP 43:2020, General Chapter 62)
Detection of E. coli is conducted using systems like the Bio-Rad iQ-Check, ensuring the product is free from this pathogen and safe for consumption, meeting microbiological safety standards.
29. Detection of Anabolic Steroids, Nandrolone
(LC-MS/MS)
Nandrolone quantification is performed using liquid chromatography-tandem mass spectrometry (LC-MS/MS) on the Waters Xevo TQ-S Micro. Multiple Reaction Monitoring (MRM) technology provides extreme precision in detecting nandrolone and its metabolites, ensuring the product complies with safety regulations and WADA anti-doping guidelines, confirming it is free from controlled substances.
30. Detection of Anabolic Steroids, Stanozolol
(GC-MS with Electron Impact Ionization)
Stanozolol detection is conducted using the Agilent 7890B GC coupled with the 5977B MS, utilizing electron impact ionization for precise fragmentation. This technology enables nanogram-level detection, ensuring the product is free from synthetic anabolic steroids and in full compliance with WADA international standards, safeguarding product safety and integrity.
28. Detection of Anabolic Steroids, Testosterone
(GC-MS/MS)
Testosterone is quantified with high precision using gas chromatography-tandem mass spectrometry (GC-MS/MS) via the Thermo Scientific TSQ 9000. This triple quadrupole system with Selected Reaction Monitoring (SRM) allows sub-picogram detection levels, ensuring compliance with physiological and regulatory standards. The method ensures the product is free from controlled substances and meets WADA's safety and anti-doping regulations.
SCIENCE & RESEARCH
STUDIES ON CREATINE MONOHYDRATE
PHZON GROUP LLC.: Innovation and Excellence in the Heart of Georgia
Stone Mountain Georgia, USA
In the charming and historical landscapes of Georgia, where the warmth of the Southern sun meets the rich tapestry of American heritage, a company emerges that blends tradition with cutting-edge innovation: PHZON GROUP LLC. Nestled in one of the most captivating and culturally vibrant regions of the United States, PHZON GROUP LLC. is dedicated to bringing the finest that science and technology have to offer to the world.
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Since its foundation, PHZON GROUP LLC. has committed itself to rigorously test, evaluate, and approve the quality of innovative ingredients entering the market. Supported by a team of passionate and dedicated scientists, the company takes pride in positioning itself at the forefront of bioscience, ensuring that every ingredient undergoes a meticulous evaluation process. This unwavering commitment to quality and advancement mirrors the spirit of Georgia's scenic rivers, symbolizing the company’s devotion to excellence.
Much like Georgia's role in shaping American history, PHZON GROUP LLC. embodies the spirit of exploration and innovation. Just as pioneers ventured into this land with a vision, the company continuously seeks new horizons, bringing discoveries that benefit humanity. The genuine Southern hospitality and integrity that Georgia is known for inspire the transparency and ethical standards with which PHZON GROUP LLC. operates.
On a global scale, PHZON GROUP LLC. stands as a symbol of innovation and authenticity. Its presence in Georgia is not merely geographical but deeply symbolic: it signifies the perfect fusion of nature’s richness with the brilliance of science, a harmonious blend of tradition and modernity.
